COMPLETE Technologist Downstream - Toronto, ON

Reference No. R2722187

Position Title: Technologist

Duration: Fixed-Term Contract (February 5, 2024- February 5, 2027) Subject to change

Department: Influenza Vaccine manufacturing, Downstream Processing

Location: Toronto, Ontario

Sanofi Vaccines

Sanofi's global vaccines business unit partners with the public health, medical and scientific communities to improve access to life-protecting vaccines and increase vaccination coverage, while striving to develop new and improved vaccines to enhance health and well-being.

At Sanofi, we chase the miracles of science to improve people’s lives.  We believe our cutting-edge science and manufacturing, fueled by data and digital technologies, have the potential to transform the practice of medicine, turning the impossible into possible for millions of people. 

Major Activities of the Job:

Execute downstream processing, sterile filtration of Influenza drug substance:

• Set up, maintain a variety of automated and manually operated equipment and perform production activities in downstream processes:  centrifugation and sterile filtration of drug substance.

• Perform troubleshooting and assessment of processes and technical problems.

• Clean-in-place (CIP), cleaning-out-of-place (COP) of downstream equipment and vessels.

• Provide training to personnel.

• Execute and verify IQ/OQ/PQ validation and cleaning verification protocols.

• Perform other duties as assigned by department   management throughout all stages of drug substance   manufacturing   related   to B200 operations (MWS, Upstream   and Downstream processes).

• Ensure all equipment, instruments and systems are properly assembled, installed, tested and maintained.

• Participate in preventive maintenance of production equipment and instruments.

Perform sampling and analytical tests- utility sampling, environmental monitoring and area-specific testing:

• Sample processed materials and perform in-process testing according to procedures.

• Deliver samples to other departments on site as required.

• Perform area-specific testing, utility sampling and environmental monitoring for production.

Maintenance of clean rooms, equipment, inspection readiness:

• Perform routine cleaning and disinfection activities in classified environments.

• Maintain and organize cleanroom in good cGMP state and ensure area is always inspection ready.

• Submit equipment/material orders and maintain inventory of spare parts, purchased materials for downstream processing.

• Maintain safe and clean work environment by following site procedures and cGMP regulations.

• Participate in facility preparation and inspection readiness, safety and process audits.

Administration of data for Influenza drug substance operations:

• Document, review and maintain production and monitoring activities for Influenza drug substance manufacturing.

• Draft, review   and revise cGMP documents (SOPs/SWIs, batch protocols, change controls, reports and other manufacturing supporting documents).

• Analyze, enter & verify data on paper based or electronic documents.

• Follow all SWI/SOPs and comply to site policies and procedures.

Participate in continuous process and equipment improvement, Health, Safety & Environment, Quality, and Inspection readiness initiatives:

• Perform and participate in continuous improvement and development projects.

• Initiate Deviations,  CCR,  CAPA  in Quality  system  as needed  and  assist until completion  as per committed due dates.

• Participate in deviation investigations and root cause analysis.

• Follow HSE SOPs, identify and minimize risks, promote safety culture.

• Comply with HSE guidelines on the disposal of waste.

Minimum Qualifications:

• Minimum three (3) years College Diploma ( Biochemistry, Microbiology, Bioengineering, Biotechnology, Chemistry, Chemical Engineering, Pharmaceutical  Sciences ) plus a minimum of one (1) year of previous relevant work experience.

• Preferred four (4) years Bachelor’s Degree ( Biochemistry, Microbiology, Bioengineering, Biotechnology, Chemistry, Chemical Engineering, Pharmaceutical  Sciences ) plus a minimum of one (1) year of previous relevant work experience.

• Purification Process for viral proteins.

• Production Equipment.

• Aseptic Technique.

• Current Good Manufacturing Practices  (cGMPs).

• Chemistry, Microbiology, Biochemistry, Mathematics.

• Computer.

• Mechanical Aptitude and Technical Writing.

• Communication / Networking.

•  Interpersonal / Teamwork.        

• Stress/Time Management and Conflict Resolution.     

Hours Of Work:

• Inclusive from Monday - Friday: 8:00 a.m.- 4:00 p.m. (Subject to change)

Pursue Progress.

Discover Extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

Watch our ALL IN video and check out our Diversity, Equity and Inclusion actions at sanofi.com!

Sanofi is an equal opportunity employer committed to diversity and inclusion. Our goal is to attract, develop and retain highly talented employees from diverse backgrounds, allowing us to benefit from a wide variety of experiences and perspectives. We welcome and encourage applications from all qualified applicants.  Accommodations for persons with disabilities required during the recruitment process are available upon request.

Thank you in advance for your interest.

Only those candidates selected for interviews will be contacted.

Follow Sanofi on Twitter: @SanofiCanada  and on LinkedIn: https://www.linkedin.com/company/sanofi 

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