COMPLETE Distinguished Scientist Investigational Toxicology - Cambridge

Position Title

Distinguished Scientist, Investigative Toxicology

Job overview

Sanofi is seeking an experienced investigative toxicologist to join our Preclinical Safety organization in a position that offers exciting and challenging scientific opportunities in a global environment. The incumbent will be responsible for contributing to the management of safety issues, advancing innovative scientific initiatives, working collaboratively to investigate mechanisms of toxicity, providing subject matter expertise as needed to support Investigative Toxicology efforts, and working transversally with colleagues across Sanofi sites to promote the interests of patient health and safety. They will provide intellectual and strategic input to characterize toxicologic liabilities and advise on strategies for advancing therapeutics to registration. The successful candidate will possess the ability to delve into toxicity findings and propose scientific hypotheses and investigative strategies to understand possible underlying mechanisms.  Critical thinking abilities are a key attribute, as is the ability to synthesize and interpret diverse forms of data and distill the key messages. The successful candidate will also work collaboratively with external vendors, ensuring scientific rigor, and participate in external consortia representing Sanofi as necessary.   

Responsibilities

• Propose and devise investigative strategies to understand mechanisms of toxicity.

• Clearly communicate investigative strategies and subsequent findings to project teams and Preclinical Safety management as necessary and provide advice on the early research program or clinical and regulatory strategy as required.

• Lead Investigative Toxicology efforts, including providing matrix management of Investigative Toxicology laboratory colleagues and facilitating appropriate internal and external resources as needed.

• Guide and oversee assessment of new and innovative tools and models and their application to Toxicology and the Sanofi portfolio.

• Work collaboratively to assist project team members to understand toxicologic and pharmacologic relevance and implication of in vivo and in vitro study findings.

• Serve as a subject matter expert and assist in authoring of regulatory submission documents and in addressing issues or queries from regulatory agencies, including proposing strategies for resolution.

• Author investigative reports for inclusion of results in white papers or regulatory submissions as needed.

• Participate in relevant external consortia or working groups to stay abreast of evolving knowledge and trends within the scientific community and the pharmaceutical industry. Represent Sanofi interests, maintaining high ethical and scientific standards.

• Author external presentations and manuscripts to contribute to the advancement of scientific knowledge.

Requirements & Qualifications

• Knowledge and experience in the field of Toxicology is required. A PhD in Toxicology, pharmacology, biology, or equivalent scientific discipline is required, with a minimum of 10-15 years of relevant research experience in a pharmaceutical or biopharmaceutical setting.

• Knowledge and experience in systems toxicology is a plus.

• Experience analyzing RNA-seq and other types of genomic data sets is also a plus. Established record of scientific contribution in peer-reviewed journals and scientific symposiums, and excellent verbal and written communication skills are required.

Terms of employment

Occasional domestic and international travel to Sanofi Research and Development sites (e.g - Paris, France; Frankfurt, Germany) and scientific conferences.  Availability to start in 1Q2024.

What makes this position unique?

The candidate will be part of a dynamic and innovative global Investigative Toxicology group at Sanofi and have opportunity to work on challenging scientific toxicological issues. There is tremendous opportunity for innovation within the role, and the global scope will provide the candidate with a rich, diverse work experience.

Benefits of working in this role

The candidate will:

• Be part of an active, innovative scientific group

• Have diverse opportunities to collaborate globally

• Be highly recognized for successes

• Receive excellent benefits and compensation

Location information

The position is based in Cambridge, MA and offers flexible working arrangements. 

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.