COMPLETE UNIV-Post Doctoral Fellow- Dr. Husain's Lab- Department of Ophthalmology - Charleston

Job Description Summary

A postdoctoral position is open in the laboratory of Dr. Shahid Husain in the Storm Eye Institute in the Department of Ophthalmology. The successful candidate will conduct research in the areas of cellular and molecular biology of retinal ganglion cell (RGC) death in glaucoma and other ocular
pathologies. The projects will be using physiological, Molecular Biology, and biochemical methods. The research projects will particularly focus on epigenetic and metabolic changes induced RGC death and neuroprotection strategies will be implemented to reduce axonal and RGC death. Our laboratory utilizes a variety of in vivo and in vitro models including acute and chronic rodent glaucoma models, isolated ocular cells from rodent and human donor eyes. Numerous techniques and procedures will be utilized in these projects including RNA Seq, Bisulfite Seq, ATAC Seq, qRT-PCR, Immunofluorescence of tissues and cells, Western Blotting, functional studies such as Electroretinograms and Optokinetic. This position will also require assisting and training of other personnel in the lab.

Entity

Medical University of South Carolina (MUSC - Univ)

Worker Type

Employee

Worker Sub-Type​

Research Grant

Cost Center

CC000988 COM Ophthalmology CC

Pay Rate Type

Hourly

Pay Grade

University-00

Pay Range

$0 - $0 - $0

Scheduled Weekly Hours

40

Work Shift

Job Description

Job Description:

A postdoctoral position is open in the laboratory of Dr. Shahid Husain in the Storm Eye Institute in the Department of Ophthalmology. The successful candidate will conduct research in the areas of cellular and molecular biology of retinal ganglion cell (RGC) death in glaucoma and other ocular pathologies. The projects will be using physiological, Molecular Biology, and biochemical methods. The research projects will particularly focus on epigenetic and metabolic changes induced RGC death and neuroprotection strategies will be implemented to reduce axonal and RGC death. Our laboratory utilizes a variety of in vivo and in vitro models including acute and chronic rodent glaucoma models, isolated ocular cells from rodent and human donor eyes. Numerous techniques and procedures will be utilized in these projects including RNA Seq, Bisulfite Seq, ATAC Seq, qRT-PCR, Immunofluorescence of tissues and cells, Western Blotting, functional studies such as Electroretinograms and Optokinetic. This position will also require assisting and training of other personnel in the lab.

Minimum Requirements:

Ph.D. or equivalent in Biochemistry, Molecular Biology, Neuroscience, Physiology, Biophysics, Cell biology, or related biomedical science. Expertise in molecular biology and cell physiology are required. A strong communication and writing skills and ability to analyze data will be required. Hands-on experience with animal handling and experimentation is also required.

Job Duties:

35% - Plan and conduct experiments on epigenetics-related experiments including RNA Seq, Bisulfite Seq, Chip Seq, qRT-PCR, working with animal models and collection of pertinent tissues (Essential).

20% - Performing immunohistochemistry, Immunoprecipitation, and Western Blotting and carryout analysis of experimental results using appropriate programs (including specialized image analysis software); organize and analyze data with appropriate statistical methods (Essential).

20% - Maintain equipment and tools used for experiments; troubleshoot technical problems and optimize experimental design; develop novel methodologies and experimental protocols; assist and train others in glaucoma research (Essential)

20% - Prepare manuscripts in close consultation with the PI for submission to peer-reviewed journals; present research results at departmental meetings, national and international conferences (Essential)

5% - Other duties as assigned.

Physical Requirements:

Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 15 lbs., unassisted. (Frequent) Ability to lift objects, up to 15 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 15 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 15 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 15 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent)

Additional Job Description

Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 15 lbs., unassisted. (Frequent) Ability to lift objects, up to 15 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 15 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 15 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 15 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required.

If you like working with energetic enthusiastic individuals, you will enjoy your career with us!

The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.

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