COMPLETE UNIV- Senior Research Associate - Department of Neurosciences: BioCM - Charleston

Job Description Summary

The brand-new MUSC Bioinformatics Core (BioCM) is seeking a superb bioinformatician to develop and use existing tools to speed the analysis of large genomics data sets. The focus of this position is to provide data analysis/computational services to the members of the Hollings Cancer Center(HCC) and MUSC research community.

The Bioinformatician will work closely with oncologists, biologists, and geneticists across HCC and MUSC developing, implementing, and applying computational tools to analyzed, visualize, and integrate local and independent next generation sequencing data. The successful candidate will need to be able to write original code for specific applications and be able to use and tailor existing software tools and analytic pipelines.

The candidate will become familiar with in-house developed code, open-source software, and contribute to open-source software projects. In addition, there may be opportunities to participate as a member of MUSC research teams. The ideal candidate must be able to work independently with limited guidance, keep meticulous records of his/her data analysis, and present results to HCC/MUSC members. The candidate may also perform related responsibilities as required by the Core Director of the MUSC, Dr. Stefano Berto.

Entity

Medical University of South Carolina (MUSC - Univ)

Worker Type

Employee

Worker Sub-Type​

Research Grant

Cost Center

CC000984 COM NEURO RES Operations CC

Pay Rate Type

Salary

Pay Grade

University-00

Pay Range

$0 - $0 - $0

Scheduled Weekly Hours

40

Work Shift

Job Description

Job Duties:

• 35%- Independently lead bioinformatics design and analyses of genetics, epigenomic, and transcriptomics datasets with minimal supervision. Independently supervise projects and interaction with collaborators.

• • 30%- Design and maintain of R packages, Python libraries, databases, and pipelines (e.g. next flow, snake make) for analyzing and manipulating research data applications including expertise with simple programming using R/Python or Java, statistical programming, web-development, and database query through SQL.

• • 15%- Provide bioinformatics support to different research groups at the MUSC. Train students and postdocs with minimal supervision.

• • 10%- Provide direct technical support and help guide, implement, and maintain further improvements to bioinformatics software, databases, and interfaces and works with the entire bioinformatics team to diagnose and fix related issues. Develop, maintain, and teach tutorials and workshops.

• • 5%- Assist in grant and manuscript drafting and figures.

• • 5%- Performs other responsibilities as required.

Minimum Training and Experience:

• ​Master/PhD in bioinformatics or computer science.

• •Desirable: 2/3 years of experience.

Preferred Skills:

• •Experience in applied NGS data analysis such as Transcriptomics (RNA-seq, scRNA-seq), Genomics (WGS/WES) and Epigenomics (WGBS, ChIP-seq,ATAC-seq); additional experience with other omics methods is a plus.

• •Demonstrable experience in programming languages required for data analysis (R and/or Python); Experience with other programming languages isof advantage.

• •A solid foundation in statistics; Experience with advance statistics (e.g. machine learning, deep learning) is of advantage.

• •Good working knowledge of Unix/Linux/MacOS.

• •Knowledge and use of cloud computing environments, specifically Amazon Web Services and familiarity with cluster (HPC) compute environments.

• •Desirable: Experience building and maintaining bioinformatics tools/pipelines; experience with scientific software development is of advantage.

MUSC Physical Requirements:

(Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift)

Ability to perform job functions in an upright position. (Continuous)
Ability to perform job functions in a seated position. (Continuous)
Ability to perform job functions while walking/mobile. (Frequent)
Ability to climb stairs. (Infrequent)
Ability to work indoors. (Continuous)
Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent)
Ability to bend at the waist. (Frequent)
Ability to twist at the waist. (Frequent)
Ability to perform 'pinching' operations. (Continuous)
Ability to fully use both hands/arms. (Continuous)
Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous)
Ability to fully use both legs. (Continuous)
Ability to reach in all directions. (Continuous)
Possess good finger dexterity. (Continuous)
Ability to maintain tactile sensory functions. (Continuous)
Ability to maintain good olfactory sensory function. (Continuous)
Ability to lift and carry 30 lbs., unassisted. (Frequent)
Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent)
Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent)
Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent)
Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent)
Ability to maintain 20/40 vision, corrected. (Continuous)
Ability to see and recognize objects close at hand. (Continuous)
Ability to see and recognize objects at a distance. (Continuous)
Ability to match or discriminate between colors. (Continuous)
Ability to determine distance/relationship between objects; depth perception. (Continuous)
Good peripheral vision capabilities. (Continuous)
Ability to maintain hearing acuity, with correction. (Continuous)
Must be ambidextrous.
Ability to perform gross motor functions with frequent fine motor movements. (Continuous)
Ability to be qualified physically (by medical personnel) for respirator use, initially and annually.
Ability to work alone in isolated areas, such as darkrooms. (Frequent)

Additional New Requirements:
Ability to obtain and maintain a valid drivers license.
Computer literacy.
Ability to work rotating shifts as required.
Ability to work overtime as required.
Ability to learn and use new processes, tools and equipment as required.

Additional Job Description

Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 30 lbs., unassisted. (Frequent) Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required.

If you like working with energetic enthusiastic individuals, you will enjoy your career with us!

The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.

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